ORGANIC CHEMISTRY INACTION ( The Design of Organic Synthesis) Tổng hợp hữu cơ - pdf 27

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VII
PREFACE TO THE FIRST EDITION
In 1975, under the title "HEURISKO. Introducci6n a la Sfntesis Org~inica",
I published a book which had been written mostly in thhe academic year 1970-71
and copies of which circulated at that time among the graduate students of the
Organic Chemistry Department (University of Barcelona). Although in the year
1969 Professor R.E. IRELAND had published his book "Organic Synthesis"
(Prentice-Hall), which had a rather classical approach, it was evident that starting
from 1967, Professor E.J.COREY, with his methodology and formalisation of the
synthetic process, had made a fundamental contribution to the systematisation of
organic synthesis which was, from a didactic point of view, a breakthrough in the
way Organic Synthesis was taught. Since in my incipient book some of COREY's
ideas were already collected, the time seemed ripe for an updating and to look for a
publisher. Finally, Editorial Alhambra (Madrid) included it in the collection
EXEDRA, a series of monographs on natural and physical sciences. One year later,
in 1976, the book by Dr. S. TURNER "The Design of Organic Syntheses"
(Elsevier, Amsterdam) was published, thus confirming the expediency of my
decision. Later on, S. WARREN published two textbooks: in 1978 a short but
really useful book for undergraduates entitled "Designing Organic Syntheses. A
Programmed Introduction to the Synthon Approach", and then, in 1982, a larger
book "Organic Synthesis: The Disconnection Approach" (both from John Wiley &
Sons, Chichester). In 1983, J. FUHRHOP and G. PENZLIN published their book
"Organic Synthesis" (Verlag Chemie, Weinheim) and finally, very recently, in the
middle of 1989, the book by E.J. COREY and X.M. CHENG "The Logic of
Chemical Synthesis" (John Wiley & Sons, New York) appeared.
In the meantime, in 1985, when I started to prepare a second edition of
"HEURISKO" I realised that my teaching experience in the last fifteen years had
changed my own perspective of the topic sufficiently so as to offer a book
essentially different, in which the principles, the strategies and the methodologies
for designing organic syntheses could be presented in a simple and yet rigorous
way to advanced undergraduate students (corresponding to the fifth year in Spanish
Universities). The decision to publish this new book in English was taken later,
when Elsevier Science Publishers became interested in the project.


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