



 !"#
 !"#
$%&'(%
$%&'(%
)*%+,
)*%+,

-./0%12
-./0%12
–
34.567(8
34.567(8
–
-6.-4790
-6.-4790

:60;<=>12
:60;<=>12

)''?
)''?

)@;0,A
)@;0,A
–
B:7C(8
B:7C(8

–
P.44790D,A
P.44790D,A
•
?37F>
?37F>
–
-.-37,A(8
-.-37,A(8
•
>>
>>
–
M. catarrhalis, H. influenzae, C. pneumoniae, M.
M. catarrhalis, H. influenzae, C. pneumoniae, M.
pneumoniae, Legionella
pneumoniae, Legionella
Q
Q
Key Bacterial Pathogens of CAP:
Key Bacterial Pathogens of CAP:
A Global Meta-Analysis
A Global Meta-Analysis
Fine MJ et al. JAMA 1996; 275(2):134-41.
•
Study cohorts: N = 127
•
Total patients: N = 33,148
•
Total patients reporting

J%V;;%NZVV;;%
J%V;;%NZVV;;%
,<[&8
,<[&8
,VF%NQV%%N
,VF%NQV%%N
\Q%V
\Q%V
0%]
0%]
\Q%VN,V
\Q%VN,V
%%VCVN)
%%VCVN)
^_`a
^_`a
,VN V;N
,VN V;N
)
)
^_a
^_a
WCV;,VN
WCV;,VN
N ;%%
N ;%%
RSTO#C0,A
RSTO#C0,A
A)A
A)A

W%VCVN,VN
W%VCVN,VN
V;N\Q%V
V;N\Q%V
\VV%V
\VV%V
i0;#
i0;#

\Y
\Y

)K%_-E./6;HO8a
)K%_-E./6;HO8a

)%_ jk:66;HO8a
)%_ jk:66;HO8a

j%;V
j%;V

ALMU
ALMU
–
J@g
J@g
–
(H>
(H>


data: N = 6866
S. pneumoniae
S. pneumoniae
66%
66%
Other
12%
Legionella
spp.
4%
M. pneumoniae
7%
H. influenzae
12%
;%F%V%V
;%F%V%V
RST
RST

G%F<[K467<L;`467
G%F<[K467<L;`467

ni+o<L%<L
ni+o<L%<L

UC0 /6±
UC0 /6±

pFV%FVFV%V
pFV%FVFV%V

)#;%r
J;%%,V%
J;%%,V%
i0;#
i0;#

/.:67nCi0<Lm&Gi
/.:67nCi0<Lm&Gi



)@;0g2`
)@;0g2`

Z#;%<L.<L*%<Lm&
Z#;%<L.<L*%<Lm&

%;\N%%%
%;\N%%%

Z#0'
Z#0'

,>mM0
,>mM0
ZVV;;%\VV
ZVV;;%\VV
RST
RST



!GY[
!GY[
–
A^<LNY;NC0;]NrFSN
A^<LNY;NC0;]NrFSN
p\jR
p\jR

%u;C%
%u;C%

vCM;%r
vCM;%r

@%r-4.467Nm
@%r-4.467Nm

i0H>
i0H>

ZR k366N%B:/6N2C(H
ZR k366N%B:/6N2C(H
TM File Infect Dis Clin NA 1998
TM File Infect Dis Clin NA 1998
)(%r^<%%
)(%r^<%%
w
w


)N Qc;Vd%VVCNQVF
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&
&
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%;WO;V±
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,r'G%
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T8&FS
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