DAI
HOC
QU6C
GIA HA
NOI
TRUCJNG
DAI
HOC KHOA HOC TLf
NHI£N
D^TAI
NGHIEN
CUfU
ANH
HUONG
CUA
AXIT
HUMIC
DEN SU Dl
CHUYEN
CUA MOT SO KIM
LOAI NANG TRONG
CAC DOI
TUONG
MOI
TRUONG
MA SO
:
QT -
03
- 27
CHU TRI

N
or/
^36
HA NOI 2005
MUC LUC
Trang
Bao cao torn
tat
Mddau
Chuong 1
Axit
humic va vai tro
ciia
no trong moi trudng
1.1
Su ton tai
ciia
axit humic trong
lir
nhien
1.2
Thanh phan va cau tao
ciia
axit humic
1.3
Tfnh chat
ciia
axit humic
1.4
Vai trd cua axit humic trong

PhU(my,
phdp xdc dinh Zn (H)
PhU(my,
phdp phdn tich As
Ket qua va thao luan
Nghien cuu kha nang hap
giu
cua axil humic ddi
\'di
Ph '
Ni^hicn
cuu anh
hUony,
cua pH
den
kha
ndnsj,
hdp
•^iil
Ph
'
Nghien cihi
dnh hudng cua thdi
i^ian
den kha
ndn_'^
hap
.i,'//?'
Nghien
ciiu

d/ih
hU(hii> chia
thdi gian den kha ndng hdp gill
3.3 Kel qua nghien cuu kha nang hap
giu'
cua axit
huinic vdi
Zn''
3.1
Nghien (
uu anh
hii'chig
cua pH
den
kha ndng hap
gift
3.2 Nghien
cUu
anh huong cua thdi gian den kha
nd/i'^
hap
;^iu
3.4 Nghien cuu kha nang hap giu cua axil humic
\
di
Cch'
4.1
Nghien cuu anh
hiuhig c
ua pH den kha ndng hdp

As
M / hoi
a\ii
huniu
khi
CO nidi
cua
Fe''
Nghien
eu'u
kha ndng hdp
giil'
A.\
cua sal
liunial
Nghien cuu anh hudng cua mot so dien
1\
den qua
trinii
hap
giu"
Cch*
Tiich cac ion kim loai tren cot chua axil
hunuc
6
Ket
luan
7
Tai
lieu tham khao

36
3X
41
41
42
42
43
45
46
49
50
BAO
CAO
TOM
TAT
Bt
TAI
•
l.Ten
de
tai;
Nghien
cAu
dnh huang cua axit humic den su di chuyen ctia
mot so kim loa nang trong cdc doi
tuang
moi
tru&ng
2.Maso;
QT-03.27

ion kim loai nang ra khoi dung dich nudc.
6. Cac ket qua dat duac
6.1
.Ket
qua khoa hoc
- Ve khd ndng phdn dng cua axit humic vai cdc kim loai nang trong
moi trudng nuac:
La mot axit
hiJu
ca chua trong phan
tir nhi^u
nhom chiic hoat dong nhu
cacboxyl,
phenolic hydroxyl, nito di vong, amino tham nen axit humic
la
mot
hgp
chat rat hoat dong ve mat hoa hoc. No co kha nang tham gia phan
ling trao doi cation, tao ket tiia, tao phiic vdi nhieu hap chat vo ca va
hiJu
ca.
Axit humic cd the tao phiic tan hoac khdng tan vdi
nhi6u
ion kim loai nang
va phdng xa.Vi vay, trong cac nguon nudc axit humic dugc xem la tac nhan
ldi keo va phan tan cac kim loai nang d trong cac nguon nudc. Kha nang
1
phan ling cua axit humic vdi cac ion kim loai nang
Pb^"",
Cu""^,

xuat hien
sir
thuy phan ciia cac ion kim loai nay. Thdi
gian phan ling dugc nghien
ciiu tir
20 den 360 phiit. Sau 20 phiit hieu suat
hap phu da dat tii 50% den 70% doi vdi ca hai loai axit. Cac chat dien ly hau
nhu khdng anh hudng den phan
ling
cua axit.
-
Ve
khd ndng su
diojg
axit humic de tdch kim loai nang khoi dung
dich nUdc.
Kha nang
sir
dung cot trao doi chiia humic dang
r^n
da dugc nghien
ciiu.
Ket qua cho thay cd the
sii
dung cot chiia axit humic dang
rdn
dugc tach tii
than biin ciia Viet Nam de tach cac ion
Pb^"^,
Cu^"^,

sir
dung
Van phdng pham
Thue khoan chuyen mdn
Vat tu hoa
chat
Quan ly hanh chinh
Hdi nghi, hgi thao, cdng tac
phi
1.000.000
d
7.000.000 d
10.000.000 d
800.000 d
2.200.000 d
XAC NHAN CUA BAN CHU
NHlfiM
KHOA HOA HOC
CHU TRI
D£
TAI
P/H
T^
~IM^^%'
jM^u.'
PUf
PGS.TS. Bui Duy Cam
XAC NHAN CUA
TRUCTNG
DAI HOC KHOA HOC TU NHIEN

- Humic acids are used most effectively in particular in the stage
subsequent to chemical treatment of water. Due to their outstanding
properties of adsorption of liphophlic substances, their high cation exchange
capacity, their ability to form hardly soluble complexes with polyvalence
cations and heavy metals and their high electron exchange capacity, hmic
acids are ideal as sorption medium for a number of water impurities and
especially for heavy metals and liphophlic substances.
In our works, we prepaired two kindes of humic acid. One is from peat of
Vietnam, one is comercial product of Wako company in Japan and compared
their adsorption properties , The complexation of humic acid with cations
Pb^"^,
Cu^"^,
Zn^"^,
Cd^"^,
As^"", As^
was
studied.The
adsorption capacity of
humic acid depends on pH value of solution and increases with increase of
pH (range from 1 to 6 ). After 20 minutes, about 70% to 98% these ions
absorbed on solid humic acid at pH
=
4.5 - 5.0 .
We have shown that humic acid packed column 9(0.15 - 0.45 mm
particle diameter) can remove 98% these ions at pH
=
4.6- 4.8. The
extraction effiences were highest for
Pb^"^,
Cu^"^and

vi vay, viec
xii
ly tach kim loai nang ra khdi cac ngudn nudc la mot nhu cau can thiet
va cap bach.
De tach kim loai nang tii dung dich cd the
sir
dung nhieu phuang phap khac
nhau. Song , phuang phap diing chat hap phu thudng dugc
sii
dung nhieu han ca.
Axit humic cd chiia nhieu nhdm chiic khac nhau nhu: cacboxyl, phenolic
hydroxyl, cacbonyl, nita di vdng, aliphatic va amino tham . Do tfnh chat hap phu, kha
nang trao doi cation, kha nang tao phiic khd tan vdi cation da hoa tri va cation ciia kim
loai nang, cung nhu kha nang trao ddi electron cao ma axit humic dugc xem nhu la
chat hap phu ly tudng cac tap chat vd ca va
hiru
ca trong nudc. Ben canh dd, axit
humic cdn dugc xem la tac nhan lam dich chuyen kim loai nang d cac ngudn nudc.
Trong dl tai nay, chiing tdi nghien
ciiu
phan
ling ciia
axit humic vdi cac kim
loai Pb, Cu, Zn, Cd, As va kha nang
sii
dung nd de tach kim loai nang ra khdi cac
nguon nudc khac nhau.
Chuong
I
AXIT HUMIC VA VAI TRO CUA NO TRONG MOI

An, Hue va dac biet cd rat nhilu d viing ddng bang sdng Cuu Long. Tdng trii lugng
than bun
ciia
Viet Nam la khoang 1.033.355.000
m\
O trong nudc ngam, cac chat humic thudng tdn tai vdi ndng do
tir 10 ppb
den
100
ppm.
1.2.Thanh phan va cau tao cua axit humic
Axit humic dugc
hinh
thanh tii qua trinh phan huy ddng thuc vat. Tuy thuoc vao
dilu kien chuyen hoa va ban chat cua ddng thuc vat ma qua trinh chuyen hoa se tao
nen cac axit humic cd ca'u tnic, trgng lugng phan tu va thanh phan hoa hgc khac
nhau.
Axit humic cd khdi lugng phan tu tii 2.000-600.000 dan vi
caebon.
Tuy thugc vao
nguon gdc ma axit humic cd thanh phan khac nhau. Tuy nhien, thanh phan chfnh
ciia
axit humic la cac nguyen td C, H,
O,
N va mdt lugng nhd cac nguyen td khac nhu S, P,
Al,
Fe. Ham lugng cac nguyen td chu yeu nay thudng chiem ty le nhu sau:
Ham lugng C
:
tii

phatic.Axit humic cd chiia cac nhdm chiic khac nhau nhu -COOH,
phenol, ali phatic, enolic hydroxyl, C=0. Axit humic la mdt td hgp cac phan
tir
hinh
thanh nhilu sgi dai d pH tha'p va cau tnic linh ddng cd nhilu
Id
hdng d pH cao. Chfnh
cac
Id
hdng nay cd the
giii
va hap phu cac cha't vd ca va huu ca mang dien tfch trai
dau.
Phan
tir
axit humic cd dang polyme, trong dd cd chiia nhiing hgp chat nhan
tham kieu phenol va cac hgp cha't chiia nita dang vdng va di vdng (indol; purin;
primidin) va cac axit amin. Cac hgp chat tham tao ra nhan tham ciia axit Humic. Cac
cSu
ndi nay cd the la
nhOng
phan
tir
rieng biet (-0-) hoac la nhdm (
-NH2-;
-CH2-)
cung cd the lien ket
true
tiep qua nguyen tu
Caebon

tir
nita chuyen vao dung dich. Dd la nhirng amit, mono hoac diamino axit. Mot sd tac gia
cdn
tim
thay ca nhung axit amin cd nhan tham purin, primidin, indol
HO,
H"
H
I
C^^N
HC
HC
^
CH
CH-
CH
^
•CH
CH
HN
HC
N
HC^
C^
^N
^CH
Primidin Indol Purin
- Nhom dinh
chitc
cua axit humic

200°C
Nhu da neu trong
phSn
tren, vi trong phan
tir
cd chiia nhdm cacboxyl va phenol
nen axit humic dugc xep vao loai axit huu ca yeu. Cac nhdm chiia axit trong phan tir
humic cd cudng do axit khac nhau, ke ca cung loai caboxyl hoac phenol nhung neu d
vi tri khac nhau se cd cudng do khac nhau. Gia tri pKa
ciia
nhdm caboxyl nam trong
khoang tir 4 - 6, cdn pKa cua nhdm phenol cd gia tri tir 9 -
11.
Su cd mat ciia cac nhan tham vdi cac electron p linh ddng va cac nhdm chiic
khac nhau lam cho axit humic cd kha nang
thiic
hien phan ling trao ddi ion, tao phiic
va oxyhoa- khu. Khi trao ddi cation, cac vi tri tren phan tir humic gan nhu dugc lap
d^y
cation hydro.
Cac cha't humic gan nhu hoan toan tfch dien am do cd chiia mot lugng
Idn
cac
nhdm chiic cacboxylic, phenolic. Do qua trinh hydrat hoa cac nhdm tich dien va luc
day
tinh
dien ma cac chat humic hoa tan d trong nudc dugc phan bd rgng han do su
thay ddi dilu kien mdi trudng. Axit humic dugc xem la cau tir quan trgng trong dat va
nudc'
Dua vao ke't qua thuc nghiem nghien

phdi ttr cdn Me la cha't tao phiic).
- Lien
ket
phdn
tU:
Tao nen khi axit humic tuang tac vdi cac oxyt
R2O3
hoac
khoang set. Vai trd
ciia
axit humic trong kieu lien ke't nay gidng nhu chat ket dfnh,
lien ket cac hat khoang trong da't lai vdi nhau.
Khi diing axit humic de ket tua dinh lugng kim
loai
thi tuang tac
ciia
axit humic
vdi kim loai la tuang tac hoa hgc
chii
khdng phai la hap phu vat ly thdng thudng. pH
cua mdi trudng cd anh hudng manh de'n do
bin
cua phiic.
Pandey A.K va cac cdng su [23] cho thay: axit humic vdi nhdm chiic hydroxyl,
phenoxyl, cacbonyl cd the tao thanh hgp chat phdi trf vdi kim loai. Nghien
ciiu
su tao
phiic d
pH=
3,5

qua trinh xir ly. Song, nhiing cdng bd vl
ling
dung thuc te
ciia
cac chat humic trong
cdng nghe mdi trudng cdn chua
nhilu.Hau
het cac nha khoa hgc da sir dung cac chat
humat de tach kim loai khdi nudc hoac tach kim loai nang trong
dat.Phan ling
giua cac
chat humic vdi chat thai hoa hgc dgc hai se xay ra khi hoa chat nay dugc thai xudng
dat.Yeu
td
chii
yeu dugc quan tam trong phan ung
ciia
axit humic vdi chat thai hoa
chat la do tan
ciia
cac vat lieu humic. Cac chat humic dich chuyen trong mdi trudng
vdi mdt lugng
Idn
la do tiep
xiic
vdi chat thai kiem vf du nudc thai tach luu huynh tir
11
san
ph^m
dau md. Cac cha't humic trong dung dich cd the dugc ke't

thuy ngan len 1000 lan. Nhu vay, neu dung axit humic de tach kim loai ra
khdi nudc bang phuang phap ke't
tiia
trong trudng hgp nay se khdng cd hieu qua.
Mot anh hudng khac cua axit humic ddi vdi kim loai la phan
ling
oxyhoa-khir.
Phan ling nay xay ra theo 2
each:
Axit humic ddng vai trd la mot tac nhan khir vdi the khir la
E^=
0,7 V gdn
bang the khir cua Fe(III).
Axit humic lam
bin
viing cac cation kim loai cd tfnh khir trong dung dich
bang phan ling tao phiic chelat va do vay lam tang kha nang khir
ciia
cac
oxoanion ( nhu
Cr07^'
,Mo04
^').
Su dich chuyen, phan
ling ciia
cac hgp chat hiru ca khdng phan
cue
trong mdi
trudng nudc chiu anh hudng cua cac chat humic tan, keo hoac khdng tan trong dd. Do
kha nang phan ling dugc vdi nhilu kim loai va cac chat hiru ca nen axit humic la mot

vdi axit humic ro
ret hon so vdi oxyt khoang. Ngugc lai, tdng ha'p phu kim loai se
Idn
han trong trudng
hgp ion kim loai cd ai luc ddi vdi oxyt khoang manh han so vdi axit humic.
Axit humic thd vdi kfch thudc hat 0,1 - 0,6mm cd the dugc diing nhu la mdt tac
nhan chiet dang ran de xir ly nudc thai cd chiia
Pb^^
Zn^^
Ni^^
Ca^^
Sn^^
Cd^%
As^\
Mg^""
trong mdi trudng axit. Hang sd
bin
dilu kien
(logK) ciia
phirc kim loai - humic
(trong than
mim)
cd gia tri tir 4,6
-
5,5. Hap dung tfch theo mg kim
loai/g
axit humic
cua cdt la 0,15 (ddi vdi
Ag"*^)
va 2,22 (dd'i vdi

Cr^^
Do tfnh chat hap phu, kha nang trao ddi cation, kha nang tao phiic khd tan vdi
cation da hoa tri va cation kim loai nang, kha nang trao ddi
ciia
electron cao ma axit
humic la chat hap phu ly tudng cac tap chat trong nudc De xir ly nudc ngam, cd the
bam axit humic long vao kenh nudc ngam.
Axit humic cd do tan giam d pH thap va cd do tan rat thap d pH
=
2. Do vay,
axit humic rat cd gia tri de lam sach nudc thai cd mdi trudng axit. Axit humic ddng
mot vai trd quan trgng trong chu trinh dia hoa cung nhu dac tinh
ciia
nhilu cau tir hoa
13
hgc trong mdi trudng bien. Axit humic cd the tao phiic vdi cation kim loai va dilu nay
dan
den su di chuyen va phan bd lai cac kim loai giiia nudc va tram tich.
Tir axit humic ngudi ta cd the che tao chat hap phu HUMASORB. Chat nay rat
cd hieu qua de tach cac kim loai nang, kim loai kiem va phdng xa, cac hgp chat huu
ca. Khi dung 0,2gam
chaft
HUMASORB vdi thdi gian phan
ling
trong 2 gid d
25°C
da
ha'p phu dugc 98% Ce, Pb trong 25ml cd ndng do Ce, Pb ban dau la 200 ppm. Ca che
tach d day gom ca 2 loai: trao ddi ion va tao phiic vdng cang .
CHLfONG 2 - THlTC NGHlfiM

biin
cua Viet Nam (dugc ky hieu la axit HA2).
Tdch vd tinh che axit humic tit
than
bun Viet Nam
- Than
biin
dugc xir ly ban dau vdi axft, hoa tan trong kilm rdi dugc ke't
tiia
lai
bang axft. Lgc, rira - lap lai cac qua trinh hoa tan trong kiem, ket
tiia
lai vdi axft. Lgc,
rira tdi pH
^
2 vai lan. Hong khd, cudi ciing say d nhiet do nhd han
80"C
- Xac dinh ham lugng axft humic theo phuang phap [7] .
14
Giii cac san pham axft humic trong
Ig
kfn. Trudc khi dung,dugc nghiln nhd tdi
kfch thudc
cdn
thiet.
•
2.3, HOA CHAT VA THUOC
THU^
Cac hda cha't dugc diing
diu

ciiu
vdi hdn hgp cac kim loai va cho chay qua cdt cd chiia axft humic
d dang hat nhd de xem xet kha nang tach chiing ra khdi ngudn nudc. Phuang phap nay
dugc ggi la phuang phap nghien
ciiu
ddng.
2.4.1.
Phuang phap nghien
cihi tinh
-
can
0,100g axft humic cua hang Wako da dugc tinh che lai va
ciia
Viet Nam,
nghiln nhd vdi kfch thudc < 0,45mm, cho vao binh tam giac 250ml.
- Lay vao cdc loai 100ml: 40ml dung dich kim loai can nghien
ciiu
cd ndng do
Img/ml,
sau dd diing
CH3C00Na,
HCl, NaOH dilu chinh pH den cac muc khac nhau
(kiem tra bang may do pH), rdi dinh
miic
50ml va dd vao binh tam giac da cd 0,100g
axft humic vira neu tren, lac
diu
trong hai tie'ng ddng hd. Tien hanh lgc qua giay lgc
bang xanh
(I^l

ngay sau khoang thdi gian da dinh.
- Tien hanh phan tfch ddi tugng nghien cuu cdn lai trong dung dich va xac dinh
chfnh xac lugng cac kim loai bi hap giu bdi axit humic
Khao sat anh hudng
ciia
mdt sd chat dien ly thudng cd trong mdi trudng nha't la
trong nudc thai cua dung dich ma den phan
ling
dugc tien hanh nhu sau;
- Cho them vao dung dich nghien ciru nhirng chat dien ly nhu:
(NH4)2S04,
K2SO4,
NaCI
,KC1.
- Tien hanh phan tfch ndng do kim loai nghien
ciiu
cdn lai trong dung dich de
tim ra lugng kim loai bi ha'p giii bdi axft humic.
2.4.2.
Phuong
phap nghien
cihi
dong
Pha hdn hgp dung dich cac kim loai nghien ciru vdi ham lugng nhat dinh rdi
dieu chinh pH thfch hgp, sau dd cho chay qua cot nhdi 4g axft humic (hat cd kfch
thudc trong khoang tir 0,15mm de'n 0,45mm, dudng kfnh cdt 12mm, tdc do chay ban
dau dieu chinh 3ml den
4ml/phiit,
nhiet do phdng khoang
32''C.

thi va chuan do bang dung dich EDTA den chuyen mau tir tfm dd sang vang hoan
toan. Trong phuang phap chuan do nay ta can tranh ndng do dung dich dem axetat cao
vi khi dd diem tuong duang se khdng rd ret.
chiing tdi nhan thay phuang phap nay cd do nhay va do chfnh xac cao. Mat
khac ham lugng kim loai dugc nghien
ciiu
d day la
phii
hgp vdi phuang phap chuan do
complexon vi nhanh va re tiln. Vdi ham lugng kim loai nhd phai diing phuang phap
do phd ha'p thu nguyen tir.
2.5.2.
Phuang
phdp xdc dinh
Cd(II)
Dixng
phuang phap chuan do Complexon vdi chi thi Xylen da cam
Phep chuan do
true
tiep
Cd"""
vdi chi thi Xylen da cam tai pH
=
5 se gap phai
khd khan ve kha nang chuyen mau
ciia
chat chi thi tai diem tuang duang. Do dd phai
dung phep chuan do ngugc bang
Zn^^
.

dj
da
asenomolipdic vang
H3[As(Mo30io)4],
rdi bi khir va chuyen thanh axft di da
asenomolipdic xanh thudng dugc ggi la xanh asenomolipdic cd cudng do mau xanh
ti
le vdi ndng do As. Nghien
ciiu
ky su tao thanh xanh asenomolipdic da chi ra rang khi
khir dang axft di da asenomolipdic vang xay ra hai qua trinh song song: tao xanh
asenomolipdic don gian va pha huy mdt phan xanh asenomolipdic. Cd the diing
hydrazinsunfat,
SnCl2,
hydroquinon, axft
asconic.
lam
chat khir.
Do do hap thu quang: Cue dai hap thu quang dang xanh asenomolipdic da khir
phu thudc vao chat khir sir dung. Do hap thu thudng dugc do d viing 700nm de'n
840nm. He sd hap thu phan tir
ciia
xanh asenomolipdic d 840nm la
2,5.10'"^.
- Thudc thir
-h
Dung djch chuan asenat: can
0,132g
AS2O3
rdi dem hoa tan trong 2 - 3ml

liic
nudc bat dau sdi trd lai. Sau dd lay cac
binh mSu
ra, lam lanh dudi vdi nudc va chuyen dinh
miic
25ml. Tie'n hanh do quang d
budc sdng 840nm, lap dudng chuan va tim nong do
ciia
As theo dudng chuan.
La'y nhung lugng chfnh xac As khac nhau vao cac cdc dugc danh sd va tie'n
hanh phan tfch bang phuang phap do quang xanh asenmolipdat tai budc sdng 840nm.
Ket qua thu dugc d hinh
2.1
dUdng
hap
thu quang
Hinh 2,1,
Du&ng
chudn do quang cua As
19
Thuc
i6
asen ton tai d hai dang
As(in)
va As(V). Phuang phap xac dinh asen
bang do quang d dang asenomolipdat xanh chi thuc hien dugc cho As(V). Vi vay, khi
xac dinh As(III)
cfc
phai dua As(III) len
As(V).Chiing

0,18
0,308
0,305
0,587
0,548
0,810
0,809
CHl/ONG
3.
K£T
QUA
vA
THAO LUAN
3.1 Nghien cuu kha nang hap gift cua axit humic ddi vdi
Pb^^
3.1.1.
Nghien
ci/u
dnh
hudtig
cua pH den khd ndng hdp giu
Pb^^
Axit humic la mdt axft yeu nen pH cd anh hudng manh den phan ling
ciia
axft
humic ddi vdi
Pb'.
De tim ra dilu kien pH tdi uu cho phan
ling
chiing tdi da khao sat vdi

3
40
0,14
29,00
11,00
0,05
4
40
0,09
18,72
21,28
0,10
5
40
0,07
15,29
24,71
0,119
5,5
40
0,08
16,00
24,00
0,115
6
40
0,06
11,40
28,56
0,14

21
trong dung dich. Nhung
d
pH
th^p
thi anh hudng rat
Idn
va kha nang hap giii cua axft
humic vdi kim loai nay giam
dk\,
^
Tuang tu
thf
nghiem nghien
ciiu
vdi
HAI
,
chiing
tdi
da khao
sat
anh hudng
ciia
pH den phan
ling ciia
HA2 vdi
Pb^"".
Ket qua thu dugc nhu sau:
Bang

4
40
0,09
19,50
20,50
0,10
5
40
0,08
15,70
24,30
0,12
5,5
40
0,08
15,60
24,40
0,12
6
40
0,06
12,50
27,50
0,13
E
M
: Luong
Pb^*
bj hap
giur(mg)

thuc hien dugc de'n
pH =
4,5-5,5.
Khi
mdi trudng
pH cao han
dung dich
Pb^""
se bi
thuy phan.
TCr
ket qua
tren
ta cd the
nhan dinh rang trong khoang
pH
tir
4,5
- 5,5 la
thfch
hgp cho kha nang phan
ling ciia
Pb^"*"
vdi axit humic
3,1,2, Nghien citu
dnh
hudng cua
th&i
gian den
khd

th&i
gian
den
khd ndng hdp
giitPb^^
cua
HAI dpH ^
4,5
Thcri
gian (phut)
Mpbbandau(mg)
Cpbconla.
(mDlg)
Mpbconlai (mg)
Mpbbihapgia(mg)
Cpb
b,
hap
g.Q
(mDlg)
10
50
0,14
28,39
21,61
0,10
20
50
0,12
25,07

29,18
0,14
240
50
0,10
19,68
30,32
0,15
360
50
0,09
19,48
30,52
0,15
23