DAr
HQC
GrA
Harr0r
Qudc
VIETNAL
NATI0NAIttt'ttVERSITy,
HAXOT

t55N
0 8 6.6g 6t z

ffiffiffi
JE URNAL

KH0A
H0GTUN
NMURAL SCIE


TAP CHI KHOAHgC DHQGHN,KHTN & CN, T.XXil],S6 1,2007

NGHIENctltr tdxc Hdp vA rrTA NANCUCCHfr

alv tvroNKrMLoAr ctia uOr sd nnNzoyLHIDRAZoNoHit*o"taoroPHENoN
Nguy6n

Minh Thio,

Ph4m Vin


104,92,69,55, 50.
Tr) cic sdliQu tr6n, c6 thd d6n ra so dd phAn minh chfnh cria c6c hidrazon nhu sau:

Tqpchi KhoahocDHNH N, KI{TN & CN, Tffi II, SdI, 2007


Nghi0ncfu t6nghqp vl khi nangrlc chdin mbnkim loqi...

7l

d\(o'

"'t\l\f

:N-M.."-[fuil+
cHr

\/

M*
(\(""
u^
H'c-\l\;-,.-.

,/"

v 't:v-*"-.-@*-h".

ILco.
.,

2

3

4

5

6

7

29,40

5,76

4,26

9,00

8,28.

7,80

6,70

3,86

5,52


71,84

I

Nhrr v{y, t{t cA c6c hidrazon tdng hgp drrgcd6luc6 khi ning itc chd dn mdn kim
Io4i v6i mrlc dQkh6c nhau (hiQusudt b6o vQtt 69,4- 86,7%).

Th{c nghiQm
* Tdng hqp S-vi 4- metyl - 2- hidroxi axetophenon( ILz )[5]
Di til o-cresolvi m-cresol qua phin rlng este h6a bing anhidrit axetic rdi chuydn
vi Fries tidp theo [5] v6i Alcls khan lhm x6c tdc.
HiQusudt: gO-g4%
t!:2l|oC
o-cresylaxetat
m-cresylaxetat

HiQusudt: 9Q- 94o/o

t! :2l0oC

3-metyl-2-hidroxiaxetophenon

HiQu sudt:75%

t! :1750C

4-metyl-2-hidroxiaxetophenon

HiQusudt: 71%



t!:2L5oC

4) Metyl m,nitrobenzoat

HiQusudt:65%

t!:78-790C

5) Metyl p-nitrobenzoat

Hi6u sudt: 65%

to,296-97oC

1) Hidrazit ctra axit benzoic

HiQu sudt: 80%

-l
{ : 109 lOoC

2) Hidrazit cria axit m-toluic

HiQu su{t: 93%

t! :90-910C

3) Hidrazit cira axit o-nitrobenzoic


Dd tdng hqp duo.cmQt ddy hidrazon di tt c6c metyl o-hidroxiaxetophenon v(n che
hidrazit cria e6c axit benzoic thd. Cdu t4o cria cdc sin phdm di du-o.cx6c clinh nhi phd
hdng ngoqi, cQnghtr8ng tt pr6ton vi phdkhd lugng. T{t ci c6c hidrazon nhgn dugc ttdu
c6 khA ning rlc chdin m6n th6p CT-3 trong mOitrudng HCI 2M.
u

TAr LrSU THAL KHAO
1.

A. S. Fouda, M. M. Gauda, S. I. Abd El-Ratimarr, Bull. Korean Chem, Soc., Vol.21, 1f11,
(2000), 1085.
Nguy6n Minh Th6o, Vfr Minh TAn, Phqm Vdn Nhitu, Tgp chi H6a hgc,T.42, If3(2004), tr.
3 11 .
Ph4m VIn Nhi6u, Vfr Minh Tdn, Nguy6n Minh Thho, Tg.p chi Ph6n tich H6a, L! vd Sinh
hgc, T. 9, lf2(2004), tr. 42.

Tqpchi Khoaho.c DHQGHN, KHTN & CN, T)N II, SdI, 2M7


Nguy€nMinhThio,PhemVnnNhiOu...

74

4.

NguySn Minh Th6o, Phgm Vin Nhi€u, Nguy6n Mgnh Cuing, Tqp chi H6a hgc vd tng
dVng, T{7 (2005), tr. 35.

5.


CONTENTS
l .

Vu Duc Minh. Some new experiment results applying combination
of the electrical souriding methods in order to discover old
vestiges

2,

Le Duc Manh, Nguyen Thi Huong Giang. Appiication of PCR
techniquefor detectionof Salrnonellain polluted surfacewater
Lz

3.

Pham Ngoc Lan, Luu Van Boi. Amphiphilic polyurethanes with a
novel peg-containing chain extender part
I: Synthesis and

characterization)
4.

Hoang Thu Ha, Pham Thi Tran Chau. Study on trypsin inhibitor
(tI) and chymotrypsin inhibitor (KI) from seeds of blue dragon
(Hylocereus
undatus (Haw.)Britton & Rose).....

D .

Mai Trong Nhuanr, Tran Dang Quy, Nguyen Tai Tue, Dao