Rối loạn chuyển hóa Lipid
PGS.TS Đỗ Hòa Bình
Môc tiªu
         

      ! " #$ %
&
' (  )      %
*+*&
,-.+!"#$/-
01&2
1. §¹i c¬ng.
3-456&'7&
)8
- Triglycerid 9&:);
- Phospholipid
- Cholesteron.

1.1. Tiªu ho¸, hÊp thu

1.2. Sö dông, vËn chuyÓn
trong m¸u


VËn chuyÓn phospholipid vµ cholesterol:
díi d¹ng lipo-protein (LP)

   3* 7 < % " 
+=*+*>?
&@4A2B.* 
C3(D*7B

1.4.1. Hormon lµm t¨ng tho¸i ho¸ lipid
=
N*! * 9O 4 P 
$&! " -;8 Q R    +*
&@&:→SSN7%PT=UV
=
W+*++X7Q4-R
=
Y*++&%NWM
→2*Z&+*→$7SSNO[
&@&:
=
\M X    1   # +R %
  G &E   -  1  1
SSNG&<

1.4.2. Hormon kÝch thÝch tæng hîp
triglycerid
= L+81] &2   *+*  P
^NH(M

 & %  &] *=WN! 
.)tæng hîp acid bÐo
= (+ _8 % ` A !  4
+4-a

2. Rèi lo¹n chuyÓn ho¸ lipid.
2.1. T¨ng lipid m¸u.
•
b45!V&`

%*+*
    % β= 3(  a β= 3( 7 On& % * 
*+*
    % aβ= 3( On& % 4: P! *!
*+*
+ Di truyÒn8T
=
Gi¶m LP:
go@ 7 β=! & h!  . 
a!)*G!!&
P
g\$&α=8X7)1!$&α=
! %J3H3  &   )
*+*G&@
l
2.3. Rèi lo¹n chuyÓn ho¸
cholesterol
T¨ng cholesterol m¸u

+ Nguyªn nh©n:
*H%a<%*+*8
1[<!&:1"!!p
qHOi&1$!<2-8j
&"
q%18%I?&814
5Q!<"4
qH"&8%!)
1E*
+ HËu qu¶:
W*+* &% Oi  +r